Dhami began her career in modeling with print and television advertisements before debuting in the entertainment industry with her appearance in the music video for Saiyyan Dil Mein Aana Re. Her first role was in the Star One show Dill Mill Gayye, where she portrayed the bubbly Dr. Muskaan. She then appeared as the female lead for the popular Star Plus show Geet - Hui Sabse Parayi opposite Gurmeet Choudhary, where their pairing and her performance garnered widespread attention. Dhami also made a brief appearance through her dance performance for the show Na Bole Tum Na Maine Kuch Kaha. She then played the titular role in her most popular Colours TV serial Madhubala – Ek Ishq Ek Junoon opposite Vivian Dsena. Following her success as Madhubala, the actress took a year long break from television before returning to star as Rani Gayatri Devi in Ek Tha Raja Ek Thi Rani on Zee TV.